Before that though, with 100 kilometers to go a
mass crash marked the race, sending many of the main favourites down to the ground when a huge gust of crosswind took an Alpecin-Fenix rider down at the head of the peloton. The likes of Tiesj Benoot, Michael Matthews and Matej Mohoric abandoned, Julian Alaphilippe and
Alejandro Valverde having to chase back and even Tadej Pogacar hit the deck. Eventually the Alaphilippe group returned to the front of the race.
At Monte Sante Marie, where the race was expected to blow up, Tadej Pogacar launched a daredevil move on one of the downhill sections and got a gap with 50 kilometers to go. INEOS' Carlos Rodriguez was the only rider briefly trying to bridge across, but without success.
The peloton stuck together but the gap grew very quickly up to a minute, and hit a maximum of 1:40. Quick-Step, with Alaphilippe, Movistar and Trek put on a chase that didn't quite cut the gap but kept it stable. At Vico d'Arbia with 23 kilometers to go Kaspe Asgreen launched an attack in the peloton, followed by Narvaez, Simmons, Valverde and Wellens, and brought the gap down to a minimum of 50 seconds.
But the gap would not come down more than that, Asgreen attacked at Colle Pinzuto later going solo, being joined at Le Tolfe by Alejandro Valverde who then organized a chase, but one that would not eventually succeed.
Pogacar had time to enjoy the final ascent of the Via Santa Caterina, and took a victory in style at the Piazza del Campo. Alejandro Valverde and
Kasper Asgreen wrapped up the podium shortly after.